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Directorate for Biological Sciences (BIO)

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Directorate for Biological Sciences (BIO)

NSF reorganization

Updates to reflect the new organizational structure of BIO are in progress. Some information on this page may no longer be current.

Directorate for Biological Sciences (BIO)

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Division of Biological Infrastructure (BIO/DBI)

Division of Environmental Biology (BIO/DEB)

Division of Integrative Organismal Systems (BIO/IOS)

Division of Molecular and Cellular Biosciences (BIO/MCB)

Emerging Frontiers Office (BIO/EF)

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The U.S. National Science Foundation Directorate for Biological Sciences (BIO) supports research and education that advances understanding of all forms of life at all scales — from cells to ecosystems and across space and time.

Learn more about BIO

BIO updates

NSF partners with NIST and Schmidt Sciences to support bioeconomy Scholars-in-Residence

June 18, 2026

Update from the Assistant Director

June 16, 2026

View more updates

Recent funding opportunities

Program

Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)

Next Required Due Date: November 4, 2026

PostedJuly 21, 2026

Dear Colleague Letter

Advancing Artificial Intelligence (AI) Agent Ecosystems through the National Science Foundation Pathways to Enable Secure Open-Source Ecosystems (NSF PESOSE) Program

Next Required Due Date: See letter for details

PostedFebruary 20, 2026

Program

Pathways to Enable Secure Open-Source Ecosystems (PESOSE)

Next Required Due Date: September 1, 2026

PostedFebruary 19, 2026

Program

National Quantum and Nanotechnology Infrastructure (NQNI)

PostedFebruary 13, 2026

View all BIO opportunities

Explore BIO

Division of Biological Infrastructure (BIO/DBI)

Invests in the innovation and capacity-building of cutting-edge research infrastructure for fundamental biological science including human capital, technologies, institutes and centers and mid- to large-scale facilities.

Division of Environmental Biology (BIO/DEB)

Supports research and training on evolutionary and ecological processes acting at the level of populations, species, communities and ecosystems.

Division of Integrative Organismal Systems (BIO/IOS)

Supports research aimed at improving understanding of organisms as integrated units of biological organization.

Division of Molecular and Cellular Biosciences (BIO/MCB)

Supports research on the fundamental properties of living systems at the atomic, molecular, subcellular and cellular scales.

Emerging Frontiers Office (BIO/EF)

Supports multidisciplinary research opportunities and networking activities that arise from advances in disciplinary biological research.

Upcoming events

Wednesday, September 16, 2026, 1:00 p.m. – 2:00 p.m.

NSF BIO Virtual Office Hour: Updates from the NSF Directorate for Biological Sciences

Q&As and information sessions

Please join the U.S. National Science Foundation Directorate for Biological Sciences for a directorate-wide virtual office hour.

Thursday, October 15, 2026, 1:00 p.m. – 2:00 p.m.

NSF BIO Virtual Office Hour: Updates from the NSF Directorate for Biological Sciences

Q&As and information sessions

Please join the U.S. National Science Foundation Directorate for Biological Sciences for a directorate-wide virtual office hour.

View all BIO events

View all past BIO events

BIO news

NSF News

July 7, 2026

NSF launches Project Triad to advance quantum technology for real-world applications

NSF News

June 24, 2026

NSF selects five additional teams in National Quantum Virtual Laboratory design competition

Podcast

June 16, 2026

Podcast: Combating antibiotic resistance with AI

More BIO news

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Publication date: August 30, 2021

Last updated: June 30, 2025

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